Table 2 Operative profile of mastectomies
Partial mastectomy | Quadrantectomy | |||||
|---|---|---|---|---|---|---|
Remifentanil | Non-remifentanil | P value | Remifentanil | Non-remifentanil | P value | |
n = 98 | n = 133 | n = 56 | n = 156 | |||
Blood loss, ml | 60 [30, 94] | 90 [50, 165] | < 0.001 | 90 [30,163] | 140 [74, 220] | 0.001 |
Mean SBP, mmHg | 98 ± 11 | 115 ± 14 | < 0.001 | 100 ± 11 | 115 ± 14 | |
Mean MBP, mmHg | 74 ± 9 | 86 ± 11 | < 0.001 | 74 ± 9 | 86 ± 11 | < 0.001 |
Mean HR, bpm | 71 ± 12 | 79 ± 12 | < 0.001 | 71 ± 11 | 80 ± 13 | < 0.001 |
Anesthesia time, min | 188 ± 38 | 206 ± 43 | < 0.001 | 220 ± 47 | 238 ± 42 | 0.006 |
Operative time, min | 138 [115, 163] | 147 [126, 182] | < 0.001 | 167 [139, 190] | 179 [150, 211] | 0.056 |
Infusion volume, ml | 1300 [962, 1500] | 1500 [1200, 1800] | < 0.001 | 1500 [1088, 1863] | 177 [1300, 2000] | 0.031 |
Re-operation for bleeding, n (%) | 0/98 (0) | 1/133 (0.8) | 1 | 0/56 (0) | 1/ 156 (0.6) | 1 |
Intraoperative drug using, n (%) | ||||||
Ephedrine | 40/98 (41) | 22/133 (17) | < 0.001 | 17/56 (30) | 21/156 (13.5) | 0.008 |
Phenylephrine | 1/98 (1.0) | 0/133 (0) | 0.42 | 0/56 (0) | 1/156 (0.6) | 1 |
Atropine | 41/98 (42) | 11/133 (8.3) | < 0.001 | 21/56 (38) | 34/156 (22) | 0.032 |
Fentanyl | 1/98 (1.0) | 2/133 (1.5) | 1 | 2/56 (3.6) | 2/156 (1.3) | 0.29 |
Pentazocine | 0/98 (0) | 4/133 (3.0) | 0.14 | 0/56 (0) | 2/156 (1.3) | 1 |
Flurbiprofen axetil | 59/98 (60) | 52/133 (39) | 0.002 | 38/56 (68) | 42/156 (27) | < 0.001 |
Diclofenac suppository | 5/98 (5.1) | 7/133 (5.3) | 1 | 4/56 (7.1) | 30/156 (19) | 0.035 |
Remifentanil infusion speed, mcg/kg/min | 0.16 [0.11, 0.25] | 0.21 [0.13, 0.29] | ||||
Inhaled anesthetics | ||||||
Nitrous oxide–oxygen–sevoflurane* | 3/98 (3.1) | 107/133 (80) | < 0.001 | 1/56 (1.8) | 138/156 (89) | < 0.001 |