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Table 2 Operative profile of mastectomies

From: Protective effect of remifentanil on blood loss in endoscopic subcutaneous mastectomy: a retrospective study

  Partial mastectomy Quadrantectomy
Remifentanil Non-remifentanil P value Remifentanil Non-remifentanil P value
n = 98 n = 133   n = 56 n = 156  
Blood loss, ml 60 [30, 94] 90 [50, 165] < 0.001 90 [30,163] 140 [74, 220] 0.001
Mean SBP, mmHg 98 ± 11 115 ± 14 < 0.001 100 ± 11 115 ± 14  
Mean MBP, mmHg 74 ± 9 86 ± 11 < 0.001 74 ± 9 86 ± 11 < 0.001
Mean HR, bpm 71 ± 12 79 ± 12 < 0.001 71 ± 11 80 ± 13 < 0.001
Anesthesia time, min 188 ± 38 206 ± 43 < 0.001 220 ± 47 238 ± 42 0.006
Operative time, min 138 [115, 163] 147 [126, 182] < 0.001 167 [139, 190] 179 [150, 211] 0.056
Infusion volume, ml 1300 [962, 1500] 1500 [1200, 1800] < 0.001 1500 [1088, 1863] 177 [1300, 2000] 0.031
Re-operation for bleeding, n (%) 0/98 (0) 1/133 (0.8) 1 0/56 (0) 1/ 156 (0.6) 1
Intraoperative drug using, n (%)
 Ephedrine 40/98 (41) 22/133 (17) < 0.001 17/56 (30) 21/156 (13.5) 0.008
 Phenylephrine 1/98 (1.0) 0/133 (0) 0.42 0/56 (0) 1/156 (0.6) 1
 Atropine 41/98 (42) 11/133 (8.3) < 0.001 21/56 (38) 34/156 (22) 0.032
 Fentanyl 1/98 (1.0) 2/133 (1.5) 1 2/56 (3.6) 2/156 (1.3) 0.29
 Pentazocine 0/98 (0) 4/133 (3.0) 0.14 0/56 (0) 2/156 (1.3) 1
 Flurbiprofen axetil 59/98 (60) 52/133 (39) 0.002 38/56 (68) 42/156 (27) < 0.001
 Diclofenac suppository 5/98 (5.1) 7/133 (5.3) 1 4/56 (7.1) 30/156 (19) 0.035
Remifentanil infusion speed, mcg/kg/min 0.16 [0.11, 0.25]    0.21 [0.13, 0.29]   
Inhaled anesthetics
 Nitrous oxide–oxygen–sevoflurane* 3/98 (3.1) 107/133 (80) < 0.001 1/56 (1.8) 138/156 (89) < 0.001
  1. SBP intraoperative systolic blood pressure; MBP intraoperative mean blood pressure; HR intraoperative heart rate
  2. Continuous variables with normal distribution and with skewed distribution were expressed as mean ± SD and median [25%, 75%]. Categorical variable (ASA-PS) was expressed as number (%). Continuous variables were analyzed using Student’s t test or the Mann–Whitney U test as long as appropriate. Categorical variables were analyzed using Fisher exact test
  3. *One inhaled anesthetic other than nitrous oxide–oxygen–sevoflurane was oxygen–sevoflurane
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