The use of activated partial thromboplastin time versus antifactor Xa assay in monitoring continuous unfractionated heparin infusion therapy in obstetric intensive care unit

Ain-Shams Journal of Anesthesiology

Table 1 Weight-based nomogram for continuous intra-vascular UFH infusion

aPTT	Dose adjustment
Less than 35 s	80 U/kg re-bolus and increase infusion rate by 4 U/kg/h
35–49 s	40 U/kg re-bolus and increase rate by 2 U/kg/h
50–70 s	No change
71–90 s	Decrease infusion rate by 2 U/kg/h
More than 90 s	Hold infusion for 1 h and decrease infusion rate by 4 U/kg/h