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Table 3 Showing GRADE ranking

From: The conundrum of guidelines, recommendations, and strength of recommendation

Recommendation

What it implies?

High

Confident that the effect in the study reflects the actual effect.

Moderate

Quite confident that the effect in the study is close to the true effect, but it is also possible it is substantially different.

Low

True effect may differ significantly from the estimate.

Very low

True effect is likely to be substantially different from the estimated effect.