Half-dose sugammadex with neostigmine versus full-dose sugammadex for reversal of rocuronium in laparoscopic bariatric surgery

Ain-Shams Journal of Anesthesiology

Table 4 Muscle relaxant recovery profile in both groups for patients who received reversal within less and more than 15 minutes after the last dose of rocuronium

Variable	NS group (n = 12)	S group (n = 13)	95% CI of mean difference	P value
Anesthesia Duration
< 15 minutes	108.25±12.66	115.43±26.12	-24.3 , 9.9	.39^a
>15minutes	118.38±10.13	126.58±31.82	-27.4,11	.39^a
Surgery Duration
< 15 minutes	100.8 ± 12.56	108.6 ± 26.44	-25.1, 9.6	0.36^a
>15minutes	112 ± 10.6	119.6 ± 32.5	-27.2, 12.1	0.41^a
Et- isoflurane Conc. at the end of surgery
< 15 minutes	1.34±.32	1.53±.28	-0.44,0.05	0.12^a
>15minutes	1.49±0.29	1.28±0.36	-0.06 , 0.5	0.12^a
Total dose (mg)
< 15 minutes	82.5±9.89	91.92±26.89	-26.4,7.6	0.26^a
>15minutes	93.08±9.9	88.33±16.97	-7.1,16.6	0.41^a
D. R - 90% TOF (seconds)
< 15 minutes	385.1 ± 74.9	307.1 ± 97.1	5.8 , 150.1	0.04^*,a
>15minutes	287 ± 98.9	280 ± 94.7	-73.2, 87.3	0.89^a
D. R-Extubation (seconds)
< 15 minutes	472.0 ±78.6	384.7 ± 99.0	12.9, 161.7	0.04^*,a
>15minutes	384 ± 98.5	366.6 ± 83.3	-58.5 , 93.1	0.65^a

Data are expressed as mean and standard deviation. 95% CI: 95% confidence interval. ^aMann Whitney independent samples test. ^*p value is significant when ˂ 0.05. Abbreviations: group (NS) half dose sugammadex plus neostigmine, group (S) full dose sugammadex group, Et End tidal, Conc. Concentration, D.R - 90% TOF duration (seconds) between IV reversal and 90% TOF, D.R-Extubation Duration between IV reversal and tracheal extubation