Intraoperative infusion of lidocaine 2% reduces postoperative fentanyl requirements for pain control in renal transplantation surgery

Ain-Shams Journal of Anesthesiology

Table 6 Preoperative (heart rate HR and mean blood pressure MBP)/intraoperative (heart rate HR and mean blood pressure MBP)/recovery (heart rate HR and mean blood pressure MBP)

Type of patients	No. of patients	Preoperative HR (b/min): mean ± SD	p value
Lidocaine group	25	82.32 ± 6.908	0.032
Fentanyl group	25	86.28 ± 5.675	0.032
Type of patient	No. of patients	Preoperative MBP (mmhg): mean ± SD	p value
Lidocaine group	25	96.44 ± 6.777	0.001
Fentanyl group	25	103.28 ± 6.478	0.001
Type of patient	No. of patients	Intraoperative HR (b/min): mean ± SD	p value
Lidocaine group	25	61.92 ± 6.075	<0.001
Fentanyl group	25	89.32 ± 5.907	<0.001
Type of patients	No. of patients	Intraoperative MBP (mmhg): mean ± SD	p value
Lidocaine group	25	74.28 ± 6.655	< 0.001
Fentanyl group	25	104.08 ± 7.182	< 0.001
Type of patients	No. of patients	Recovery HR (b/min): mean ± SD	p value
Lidocaine group	25	73.32 ± 7.169	< 0.001
Fentanyl group	25	111.12 ± 6.597	< 0.001
Type of patients	No. of patients	Recovery MBP (mmhg): mean ± SD	p value
Lidocaine group	25	74.28 ± 6.655	< 0.001
Fentanyl group	25	107.64 ± 7.979	< 0.001

Preoperative hemodynamics measurement (regarding heart rate and mean blood pressure) showed no significant difference between the two groups. Overall, the mean intraoperative heart rate and MAP in the fentanyl group remained significantly higher statistically during the entire infusion period than that in the lidocaine group (p < 0.001) but within clinically acceptable range. During the recovery period, heart rate and Mean blood pressure showed higher levels in fentanyl group in comparison to lidocaine group with significant difference of p value < 0.001.