|
Time
|
Group D (N = 22)
|
Group C (N = 23)
|
P value
|
Effect of group D relative to group C
|
|---|
|
Mean ± SE
|
95% CI
|
|---|
|
Heart rate (beats/min), mean ± SD
|
|
Baseline
|
78.3 ± 14.0
|
76.1 ± 19.4
|
^0.661
|
2.2 ± 5.1
|
− 8.0–12.4
|
|
Sk. Inc.
|
65.2 ± 8.8
|
66.8 ± 15.6
|
^0.677
|
− 1.6 ± 3.8
|
− 9.3–6.1
|
|
1/2 h
|
65.9 ± 8.5
|
66.5 ± 15.2
|
^0.869
|
− 0.6 ± 3.7
|
− 8.1–6.8
|
|
1 h
|
65.9 ± 7.8
|
67.2 ± 13.4
|
^0.703
|
− 1.3 ± 3.3
|
− 7.9–5.4
|
|
1 1/2 h
|
64.8 ± 8.1
|
67.8 ± 14.5
|
^0.391
|
− 3.1 ± 3.5
|
− 10.2–4.1
|
|
2 h
|
66.4 ± 8.3
|
67.5 ± 12.2
|
^0.724
|
− 1.1 ± 3.1
|
− 7.4–5.2
|
|
PACU
|
73.6 ± 7.7
|
76.5 ± 16.3
|
^0.456
|
− 2.9 ± 3.8
|
− 10.6–4.8
|
|
After 1 h PO
|
73.6 ± 7.7
|
76.5 ± 16.3
|
^0.456
|
− 2.9 ± 3.8
|
− 10.6–4.8
|
|
After 2 h PO
|
72.7 ± 7.8
|
74.6 ± 10.5
|
^0.501
|
− 1.9 ± 2.8
|
− 7.5–3.7
|
|
After 6 h PO
|
73.0 ± 9.7
|
75.8 ± 12.5
|
^0.403
|
− 2.8 ± 3.3
|
− 9.6–3.9
|
|
After 12 h PO
|
74.5 ± 9.1
|
91.3 ± 12.0
|
^0.041*
|
− 6.7 ± 3.2
|
− 13.1–0.3
|
|
After 24 h PO
|
76.1 ± 9.2
|
82.0 ± 8.2
|
^0.031*
|
− 5.8 ± 2.6
|
− 11.1–0.6
|
|
Mean blood pressure (mmHg), mean ± SD
|
|
Baseline
|
102.5 ± 13.
|
95.1 ± 11.3
|
^0.053
|
7.4 ± 3.7
|
− 0.1–14.9
|
|
Sk. Inc.
|
88.9 ± 9.4
|
81.1 ± 16.3
|
^0.057
|
7.8 ± 4.0
|
− 0.3–15.8
|
|
1/2 h
|
88.9 ± 9.4
|
81.1 ± 16.3
|
^0.057
|
7.8 ± 4.0
|
− 0.3–15.8
|
|
1 h
|
88.9 ± 9.4
|
81.1 ± 16.3
|
^0.057
|
7.8 ± 4.0
|
− 0.3–15.8
|
|
1 1/2 h
|
88.9 ± 9.4
|
81.1 ± 16.3
|
^0.057
|
7.8 ± 4.0
|
− 0.3–15.8
|
|
2 h
|
88.9 ± 9.4
|
81.1 ± 16.3
|
^0.057
|
7.8 ± 4.0
|
− 0.3–15.8
|
|
PACU
|
88.9 ± 9.4
|
81.1 ± 16.3
|
^0.057
|
7.8 ± 4.0
|
− 0.3–15.8
|
|
After 1 h PO
|
96.5 ± 8.3
|
96.3 ± 9.9
|
^0.956
|
0.2 ± 2.7
|
− 5.3–5.6
|
|
After 2 h PO
|
95.9 ± 8.2
|
95.1 ± 8.6
|
^0.758
|
0.8 ± 2.5
|
− 4.3–5.8
|
|
After 6 h PO
|
96.3 ± 5.8
|
95.0 ± 8.6
|
^0.566
|
1.3 ± 2.2
|
− 3.2–5.7
|
|
After 12 h PO
|
95.9 ± 8.8
|
101.9 ± 8.8
|
^0.025*
|
− 6.0 ± 2.6
|
− 11.3–0.8
|
|
After 24 h PO
|
95.6 ± 9.7
|
102.8 ± 8.4
|
^0.010*
|
− 7.2 ± 2.7
|
− 12.7–1.8
|
|
Oxygen saturation (SpO2%), mean ± SD
|
|
Baseline
|
98.9 ± 0.9
|
98.8 ± 1.0
|
^0.766
|
0.1 ± 0.3
|
− 0.5–0.6
|
|
Sk. Inc.
|
99.3 ± 0.7
|
98.8 ± 1.0
|
^0.073
|
0.5 ± 0.3
|
0.0–1.0
|
|
1/2 h
|
99.3 ± 0.7
|
98.8 ± 1.0
|
^0.073
|
0.5 ± 0.3
|
0.0–1.0
|
|
1 h
|
99.3 ± 0.7
|
98.8 ± 1.0
|
^0.073
|
0.5 ± 0.3
|
0.0–1.0
|
|
1 1/2 h
|
99.3 ± 0.7
|
98.8 ± 1.0
|
^0.073
|
0.5 ± 0.3
|
0.0–1.0
|
|
2 h
|
99.3 ± 0.7
|
98.8 ± 1.0
|
^0.073
|
0.5 ± 0.3
|
0.0–1.0
|
|
PACU
|
99.2 ± 0.7
|
99.0 ± 0.9
|
^0.331
|
0.2 ± 0.2
|
− 0.2–0.7
|
|
After 1 h PO
|
99.2 ± 0.7
|
99.0 ± 0.9
|
^0.331
|
0.2 ± 0.2
|
− 0.2–0.7
|
|
After 2 h PO
|
99.2 ± 0.7
|
98.9 ± 0.9
|
^0.212
|
0.3 ± 0.2
|
− 0.2–0.8
|
|
After 6 h PO
|
99.2 ± 0.7
|
98.7 ± 0.9
|
^0.052
|
0.5 ± 0.2
|
0.0–1.0
|
|
After 12 h PO
|
99.2 ± 0.7
|
98.8 ± 0.8
|
^0.074
|
0.4 ± 0.2
|
0.0–0.8
|
|
After 24 h PO
|
99.2 ± 0.7
|
98.8 ± 0.8
|
^0.051
|
0.4 ± 0.2
|
0.0–0.9
|
- ^Independent t test
- *Significant
