TY - JOUR AU - Mohammed, Nayera S. AU - Habib, Mariam K. AU - Abbas, Essam A. AU - Mahmoud, Sahar M. AU - Ramadan, Ibraheem A. PY - 2020 DA - 2020/11/25 TI - Comparative study between the effect of dexmedetomidine and lidocaine infusion in lumbar fixation on hemodynamics, fentanyl requirements, and postoperative analgesia JO - Ain-Shams Journal of Anesthesiology SP - 67 VL - 12 IS - 1 AB - Spinal surgery is associated with high incidence of severe postoperative pain difficult to easy control. Appropriate treatment modalities decreased the postoperative morbidity, increased patient satisfaction, allowed early mobility, and decreased hospital costs. Lidocaine was used as intravenous additives to control intraoperative pain and decrease postoperative pain. As lidocaine, dexmedetomidine infusion associated with lower postoperative pain scores decreased the opioid consumption and its related adverse events. The aim of this double blind randomized prospective comparative study was to compare the efficacy of intraoperative dexmedetomidine versus lidocaine infusion on hemodynamics, fentanyl requirements, and postoperative analgesia among 66 patients subjected to lumbar fixation surgery and randomized into group D which received dexmedetomidine 1 μg/kg infusion over 10 min as a loading dose then 0.3–0.5 μg/kg/h after induction of anesthesia as maintenance dose and group X which received lidocaine 0.3–0.5 mg/kg/h after induction of anesthesia. SN - 2090-925X UR - https://doi.org/10.1186/s42077-020-00119-1 DO - 10.1186/s42077-020-00119-1 ID - Mohammed2020 ER -