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Table 3 Illustration of apnea, oxygen saturation, midazolam, and fentanyl requirements and pain scores

From: Lidocaine and dexmedetomidine combined infusion as an alternative to propofol for sedation in colonoscopy

Variables

Group P (N = 31)

Group D-L (N = 31)

P-value

Effect size

Dex.-lidocaine relative to propofol

Mean ± SD

95% CI

Apnea (number of attacks)

Zero

15 (48.4%)

31 (100.0%)

< 0.001

  

1

11 (35.5%)

0 (0.0%)

2

5 (16.1%)

0 (0.0%)

Intraoperative mean oxygen saturation (%)

97.8 ± 0.9

98.8 ± 0.9

< 0.001

1.0 ± 0.2

0.5–1.5

Midazolam dose (mg)

1.5 ± 0.6

3.3 ± 1.0

< 0.001

1.8 ± 0.2

1.4–2.2

Fentanyl dose (훍g)

48.4 ± 19.3

64.5 ± 23.5

0.005

16.1 ± 5.5

5.2–27.1

Pain score

(VAS 0–10)

median (1st–3rd) IQ

0.0 (0.0–1.0)

2.0 (1.0–3.0)

< 0.001

Not applicable