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Table 2 The postoperative VAS and time needed till rescue analgesia requested and the total dose of rescue analgesia given

From: Opioid-free general anaesthesia for transthoracic oesophagectomy: does it improve postoperative analgesia and other recovery criteria? A prospective randomised study

Postoperative VAS

Group (A)

OFA

Group (B)

OBA

P value

Immediate postoperative**

  

Mann-Whitney = 17.5

< 0.001*

 Range

2‑5

4‑6

 Median (IQR)

3 (2‑4)

5 (4‑6)

30 min postoperative**

  

Mann-Whitney = 9.5 < 0.001*

 Range

2‑6

5‑8

 Median (IQR)

4 (3‑5)

7 (6‑8)

2 h postoperative**

  

Mann-Whitney = 35.5

0.0012*

 Range

3‑6

5‑8

 Median (IQR)

4 (3.25‑5.75)

6 (5‑7)

4 h postoperative**

  

Mann-Whitney = 48

0.0065*

 Range

2‑6

4‑6

 Median (IQR)

3 (2‑5)

5 (4.25‑6)

6 h postoperative

  

Mann-Whitney = 95 0.45

 Range

2‑5

3‑5

 Median (IQR)

3 (3‑4)

4 (3‑4)

Number of patients needed rescue analgesia (nalbuphine)

12 (80%)

15 (100%)

X2 = 1.5

0.224

Time passed till first rescue analgesia requested (min)***

  

T = 4.35

0.001*

Mann-Whitney = 16

< 0.001

 Mean ± SD

 Range

165.8 ± 126.6

15‑360

23.0 ± 12.2

6‑45

 Median (IQR)

140 (48.75‑285)

20 (12.75‑33.75)

Total dose of rescue analgesia within first 6 h (mg) ***

  

T = 9.69

< 0.001*

 Mean ± SD

9.0 ± 6.21

26.27 ± 3.01

  1. IQR inter quartile range, T student t test, P was significant if < 0.05, *Significant