Inadvertent severe hypercapnia during general anesthesia: drop-in oxygen saturation or electrocardiography changes; which one warns us earlier?

Ain-Shams Journal of Anesthesiology

Table 1 Parameters monitoring and changes before induction of anesthesia and during the last 3 min prior to starting standard CPR based on patients’ records

	SPO2		MAP			HR		EKG
	Prior to induction of GA in room air	3 min prior to starting CPR	Prior to induction of GA	3 min prior to starting CPR	P value	Prior to induction of GA	3 min prior to starting CPR	P value	Prior to induction of GA	3 min prior to starting CPR
Case#1	≥ 95%	≥ 95%	85	88	0.17	88	55	0.018	NL	Sinus bradycardia
Case#2	≥ 95%	≥ 95%	81	79		93	49		NL	Sinus bradycardia and PVC
Case#3	≥ 95%	≥ 95%	84	88		97	48		NL	Sinus bradycardia and PVC
Case#4	≥ 95%	≥ 95%	80	82		89	53		NL	Sinus bradycardia and PVC
Case#5	≥ 95%	≥ 95%	90	88		67	49		NL	Sinus bradycardia and PVC
Case#6	≥ 95%	≥ 95%	84	85		101	44		NL	Sinus bradycardia and PVC
Case#7	≥ 95%	≥ 95%	78	85		96	56		NL	Sinus bradycardia

CPR cardio-pulmonary resuscitating, EKG electrocardiogram, GA general anesthesia, HR heart rate, MAP mean arterial pressure, NL normal rhythm of EKG, PVC premature ventricular contraction, SPO2 oxygen saturation measured by pulse oximetry