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Table 3 Comparison of the secondary outcomes between the studied groups

From: Intranasal midazolam alone versus midazolam/ketamine combination for preoperative sedation in pediatric patients undergoing ophthalmic procedures: a randomized controlled trial

 

Groups

P value

Midazolam N = 23

Midazolam/ketamine N = 23

Oxygen saturation 1 (%)

Median (IQR)

100.0

(99.0–100.0)

100.0

(100.0–100.0)

0.276

Oxygen saturation 2 (%)

Median (IQR)

100.0

(99.0–100.0)

100.0

(99.0–100.0)

0.695

Oxygen saturation 3 (%)

Median (IQR)

100.0

(99.0–100.0)

100.0

(99.0–100.0)

0.712

Oxygen saturation 4 (%)

Median (IQR)

100.0 a

(100.0–100.0)

100.0

(100.0–100.0)

0.647

Oxygen saturation 5 (%)

Median (IQR)

100.0

(100.0–100.0)

100.0

(100.0–100.0)

0.223

Pulse rate 1 (beat/min)

Median (IQR)

100.0

(95.0–103.0)

100.0

(95.0–102.0)

0.947

Pulse rate 2 (beat/min)

Median (IQR)

95.0 b

(90.0–100.0)

100.0

(95.0–105.0)

0.020*

Pulse rate 3 (beat/min)

Median (IQR)

92.0 b

(88.0–98.0)

100.0

(90.0–105.0)

0.013*

Pulse rate 4 (beat/min)

Median (IQR)

90.0 b

(85.0–98.0)

99.0

(92.0–103.0)

0.002*

Pulse rate 5 (beat/min)

Median (IQR)

88.0 b

(82.0–95.0)

98.0 b

(90.0–100.0)

0.001*

  1. IQR interquartile range
  2. *Significant at p < 0.05
  3. aIndicates significant difference from the baseline reading of oxygen saturation
  4. bIndicates significant difference from the baseline reading of the pulse rate