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Table 5 Changes in parameters of liver functions (AST, ALT, and serum bilirubin) between before and 3 days after the procedure in the two studied groups

From: Safety and efficacy of ketamine-dexmedetomidine combination versus dexmedetomidine alone in cirrhotic patients undergoing upper gastrointestinal endoscopy: a prospective controlled clinical trial

Parameter

KD1 (n = 35)

D2 (n = 35)

P value

AST(IU/L), mean ± SD

 Pre

89.3 ± 9.4

86.2 ± 9.1

0.17 (NS)

 Post

77.9 ± 8.7

74.3 ± 8.3

0.08 (NS)

ALT(IU/L), mean ± SD

 Pre

52.3 ± 5.1

51.8 ± 4.9

0.68 (NS)

 Post

44.8 ± 5.3

45.3 ± 4.7

0.68 (NS)

Bilirubin (mg/dl), mean ± SD

 Pre

2 ± 0.2

2.1 ± 0.3

0.11 (NS)

 Post

1.7 ± 0.1

1.8 ± 0.3

0.07 (NS)

  1. KD1 ketamine-dexmedetomidine group, D2 dexmedetomidine group
  2. AST aspartate aminotransferase; ALT alanine aminotransferase
  3. *Significant; NS non-significant