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Table 1 Demographic characteristics, medical history, operative duration, sevoflurane consumption, recovery time, intra-operative adverse events, first request of analgesia, incidence of delirium, and hospital stay

From: Effect of intraoperative dexmedetomidine on postoperative cognitive functions of elderly patients undergoing total laryngectomy

 

Dexmedetomidine group (n= 91)

Control group (n= 91)

95% CI

P

Age (years)

67.98 ± 3.370

69.02 ± 4.412

−2.19, 0.10

0.075

Gender

Male

100.0% (91)

98.9% (90)

−0.03, 0.01

0.316

Female

0.0% (0)

1.1% (1)

BMI (kg/m2)

28.11 ± 3.174

27.43 ± 3.836

−0.35, 1.71

0.194

History of DM

28.6% (26)

24.2% (22)

−0.17, 0.08

0.501

History of HTN

35.2% (32)

28.6% (26)

−0.2, 0.07

0.340

History of IHD

11.0% (10)

8.8% (8)

−0.11, 0.07

0.619

History of smoking

89.0% (81)

82.4% (75)

−0.17, 0.04

0.204

Duration of surgery (minutes)

329.3 ± 39.2

331.3 ± 43.7

−14, 10

0.749

Sevoflurane consumption (ml)

135.9 ± 39.2

166.5 ± 32.4

−41, −20

Ë‚ 0.001

Recovery time (minutes)

5.00 ± 1.789

8.85 ± 3.130

−4.59, −3.10

Ë‚ 0.001

Bradycardia

24.2% (22)

7.7% (7)

−0.27, −0.06

0.002

Hypotension

40.7% (37)

12.1% (11)

−0.41, −0.17

Ë‚ 0.001

Use of fluid bolus

36.3% (33)

8.8% (8)

−0.39, −0.16

Ë‚ 0.001

Use of ephedrine

27.5% (25)

5.5% (5)

−0.32, −0.12

Ë‚ 0.001

Time to first request of analgesia (hours)

3.73 ± 1.820

2.34 ± 1.708

0.87, 1.90

Ë‚ 0.001

Delirium

9.9% (9)

25.3% (23)

3.083

0.006

Total hospital stay (days)

6.11 ± 1.187

6.12 ± 1.163

−0.35, 0.33

0.950