| Dexmedetomidine group (n= 91) | Control group (n= 91) | 95% CI | P | |
---|---|---|---|---|---|
Age (years) | 67.98 ± 3.370 | 69.02 ± 4.412 | −2.19, 0.10 | 0.075 | |
Gender | Male | 100.0% (91) | 98.9% (90) | −0.03, 0.01 | 0.316 |
Female | 0.0% (0) | 1.1% (1) | |||
BMI (kg/m2) | 28.11 ± 3.174 | 27.43 ± 3.836 | −0.35, 1.71 | 0.194 | |
History of DM | 28.6% (26) | 24.2% (22) | −0.17, 0.08 | 0.501 | |
History of HTN | 35.2% (32) | 28.6% (26) | −0.2, 0.07 | 0.340 | |
History of IHD | 11.0% (10) | 8.8% (8) | −0.11, 0.07 | 0.619 | |
History of smoking | 89.0% (81) | 82.4% (75) | −0.17, 0.04 | 0.204 | |
Duration of surgery (minutes) | 329.3 ± 39.2 | 331.3 ± 43.7 | −14, 10 | 0.749 | |
Sevoflurane consumption (ml) | 135.9 ± 39.2 | 166.5 ± 32.4 | −41, −20 | ˂ 0.001 | |
Recovery time (minutes) | 5.00 ± 1.789 | 8.85 ± 3.130 | −4.59, −3.10 | ˂ 0.001 | |
Bradycardia | 24.2% (22) | 7.7% (7) | −0.27, −0.06 | 0.002 | |
Hypotension | 40.7% (37) | 12.1% (11) | −0.41, −0.17 | ˂ 0.001 | |
Use of fluid bolus | 36.3% (33) | 8.8% (8) | −0.39, −0.16 | ˂ 0.001 | |
Use of ephedrine | 27.5% (25) | 5.5% (5) | −0.32, −0.12 | ˂ 0.001 | |
Time to first request of analgesia (hours) | 3.73 ± 1.820 | 2.34 ± 1.708 | 0.87, 1.90 | ˂ 0.001 | |
Delirium | 9.9% (9) | 25.3% (23) | 3.083 | 0.006 | |
Total hospital stay (days) | 6.11 ± 1.187 | 6.12 ± 1.163 | −0.35, 0.33 | 0.950 |