Table 1 Exclusions criteria

1. Text articles

 Unreported findings

 It`s irrelevant

 Size of sample

 Identical research

2. Compared to other hypertonic solutions, as colloid

3. Other illnesses (coeliac or cystic fibrosis diseases)

4. Not remaining in the intensive care unit

5. Miscellaneous

6. Compared to other medications and isotonic fluids other than 0.9% saline

7. Treatment of hyponatremia

8. Prehospital/preoperative/perioperative treatment

9. Other therapies

10. In volunteers