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Table 2 Perioperative analgesic requirements and hemodynamic characteristics. Data presented as median (quartiles) and frequency (%)

From: The evaluation of the analgesic effect of intraperitoneal bupivacaine versus bupivacaine with neostigmine on postoperative pain in laparoscopic cholecystectomy: a randomized controlled double-blinded study

 

B group (n = 28)

BN group (n = 28)

p-value

Time to first analgesic request (hours)

3 (2, 6)

12 (6, 12)a

0.001

Number of patients needed intraoperative fentanyl (%)

3 (11%)

2 (7%)

0.955

Number of patients needed postoperative pethidine (%)

24 (86%)

18 (64%)

0.121

Total dose of postoperative pethidine (mg)

50 (25, 50)

25 (0, 25)a

0.002

Perioperative bradycardia (%)

2 (7%)

0 (0%)

0.150

Perioperative hypotension (%)

5 (18%)

7 (25%)

0.515

Perioperative hypertension (%)

7 (25%)

5 (18%)

0.515

Postoperative severe nausea/vomiting (%)

14 (50%)

7 (25%)

0.053

  1. aDenotes statistical significance