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Table 2 Showing statement of evidence and grade of recommendations

From: The conundrum of guidelines, recommendations, and strength of recommendation

Grades of recommendations
ARequires at least 1 prospective RCT as part of a body of literature of overall good quality and consistency addressing the specific recommendation (evidence levels Ia and Ib)
BRequires the availability of well conducted clinical studies, but no prospective, randomized clinical trials on the topic of recommendation (evidence levels IIa, IIb, III)
CRequires evidence obtained from expert committee reports or opinions and/or clinical experiences of respected authorities.
Indicates an absence of directly applicable clinical studies of good quality (evidence level IV)