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Table 1 CPIS score parameters (Schurink et al., 2004)

From: A comparative study between effect of combined intravenous and nebulized amikacin versus intravenous amikacin alone in mechanically ventilated patients with ventilator-associated pneumonia (VAP)

1. Body temperature
 ≥ 36.5 or ≤ 38.4 = 0 point
 ≥ 38.5 or ≤ 38.9 = 1 point
 ≥ 39 or < 36.5 = 2 points
2. Total leucocytic count
 ≥ 4000 or ≤ 11.000 = 0 point
 < 4000 or > 11.000 = 1 point
 Rod form ≥ 50% = add 1 point
3. Tracheal secretion
 Tracheal secretion (−) = 0 point
 Tracheal secretion with less purulence = 1 point
 Abundant purulent secretion = 2 points
4. Oxygenization
 Pa02/Fi02, mmHg >240 or ARDS (ARDS: Pa02/Fi02 < 200, Pa02/Fi02 < 200, PAWP ≤ 18 mmHg and bilateral acute infiltration) = 0 point
 Pa02/Fi02, mmHg ≤ 240 or ARDS = 2 points
5. Pulmonary infiltration in chest X-ray
 No infiltration = 0 point
 Diffuse infiltration = 1 point
 Localized infiltration = 1 point
6. Progression in pulmonary infiltration
 Radiographic progression (−) = 0 point
 Radiographic progression (+) (after the
 exclusion of HF and ARDS) = 2 points
7. Pathogenic bacteria in tracheal aspirate culture
 No or few pathogenic bacteria = 0 point
 Moderate or high levels of pathogenic bacteria = 1 point
 Pathogenic bacteria to be seen in Gram staining, add 1 point